pentobarbital will lessen the level or effect of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can lessen panobinostat concentrations by ~70% and lead to therapy failure.Contraindi
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